Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-OrzO/SymE(toxin)
Location 3681004..3681416 Replicon chromosome
Accession NZ_CP117583
Organism Escherichia albertii strain BIA_41

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag PS045_RS17845 Protein ID WP_256878708.1
Coordinates 3681004..3681345 (-) Length 114 a.a.

Antitoxin (RNA)


Gene name OrzO
Locus tag -
Coordinates 3681340..3681416 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS045_RS17825 (3677378) 3677378..3678310 + 933 WP_256878710.1 Rpn family recombination-promoting nuclease/putative transposase -
PS045_RS17830 (3678463) 3678463..3678636 - 174 Protein_3476 GntR family transcriptional regulator -
PS045_RS17835 (3678861) 3678861..3679737 + 877 Protein_3477 DUF262 domain-containing protein -
PS045_RS17840 (3679791) 3679791..3680957 + 1167 WP_256878709.1 DUF1524 domain-containing protein -
PS045_RS17845 (3681004) 3681004..3681345 - 342 WP_256878708.1 endoribonuclease SymE Toxin
- (3681340) 3681340..3681416 + 77 NuclAT_10 - Antitoxin
- (3681340) 3681340..3681416 + 77 NuclAT_10 - Antitoxin
- (3681340) 3681340..3681416 + 77 NuclAT_10 - Antitoxin
- (3681340) 3681340..3681416 + 77 NuclAT_10 - Antitoxin
- (3681340) 3681340..3681416 + 77 NuclAT_9 - Antitoxin
- (3681340) 3681340..3681416 + 77 NuclAT_9 - Antitoxin
- (3681340) 3681340..3681416 + 77 NuclAT_9 - Antitoxin
- (3681340) 3681340..3681416 + 77 NuclAT_9 - Antitoxin
PS045_RS17850 (3681573) 3681573..3682928 - 1356 WP_256878707.1 restriction endonuclease subunit S -
PS045_RS17855 (3682925) 3682925..3684514 - 1590 WP_059250861.1 type I restriction-modification system methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12414.27 Da        Isoelectric Point: 8.4921

>T271530 WP_256878708.1 NZ_CP117583:c3681345-3681004 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRKLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTTQPPATEESE
LMQSLRQVCKLSARKQKQVQEFIGVITGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271530 NZ_CP117583:3681340-3681416 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References