Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1854188..1854433 Replicon chromosome
Accession NZ_CP117583
Organism Escherichia albertii strain BIA_41

Toxin (Protein)


Gene name hokX Uniprot ID L4J2K8
Locus tag PS045_RS09075 Protein ID WP_000956460.1
Coordinates 1854188..1854340 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1854385..1854433 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS045_RS09050 1849456..1849779 - 324 WP_001246114.1 DUF3561 family protein -
PS045_RS09055 1849829..1850434 - 606 WP_256878896.1 adenylyl-sulfate kinase -
PS045_RS09060 1850434..1851861 - 1428 WP_054412002.1 sulfate adenylyltransferase subunit CysN -
PS045_RS09065 1851863..1852771 - 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
PS045_RS09070 1853025..1854062 + 1038 WP_256878880.1 alkaline phosphatase isozyme conversion aminopeptidase -
PS045_RS09075 1854188..1854340 - 153 WP_000956460.1 Hok/Gef family protein Toxin
- 1854385..1854433 + 49 - - Antitoxin
PS045_RS09080 1854604..1855338 - 735 WP_059216810.1 phosphoadenosine phosphosulfate reductase -
PS045_RS09085 1855518..1857230 - 1713 WP_273774864.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS045_RS09090 1857230..1859029 - 1800 WP_256878879.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5602.81 Da        Isoelectric Point: 7.7899

>T271522 WP_000956460.1 NZ_CP117583:c1854340-1854188 [Escherichia albertii]
MLTKYALVAIIVLCFTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 49 bp

>AT271522 NZ_CP117583:1854385-1854433 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829G7J5

Antitoxin

Download structure file

References