Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 183561..183783 Replicon chromosome
Accession NC_017625
Organism Escherichia coli DH1

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag ECDH1_RS22895 Protein ID WP_000141634.1
Coordinates 183676..183783 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 183561..183627 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECDH1_RS00880 179002..179904 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
ECDH1_RS00885 179915..180898 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
ECDH1_RS00890 180895..181899 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
ECDH1_RS00895 181929..183200 - 1272 WP_001295225.1 transporter -
- 183561..183627 - 67 - - Antitoxin
ECDH1_RS22895 183676..183783 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
ECDH1_RS00910 183870..185549 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
ECDH1_RS00915 185546..185737 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
ECDH1_RS00920 185734..187305 - 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
ECDH1_RS00925 187578..187766 + 189 WP_001063318.1 YhjR family protein -
ECDH1_RS00930 187778..188530 + 753 Protein_174 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T27151 WP_000141634.1 NC_017625:183676-183783 [Escherichia coli DH1]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T27151 NC_017625:183676-183783 [Escherichia coli DH1]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT27151 NC_017625:c183627-183561 [Escherichia coli DH1]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References