Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3775851..3776109 Replicon chromosome
Accession NZ_CP117580
Organism Escherichia albertii strain BIA_47

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS044_RS18400 Protein ID WP_000809168.1
Coordinates 3775957..3776109 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3775851..3775908 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS044_RS18385 3771801..3773048 - 1248 WP_025237694.1 hypothetical protein -
PS044_RS18390 3773202..3774552 - 1351 Protein_3593 sulfatase-like hydrolase/transferase -
PS044_RS18395 3774573..3775334 - 762 WP_001276206.1 outer membrane protein OmpK -
- 3775851..3775908 - 58 - - Antitoxin
PS044_RS18400 3775957..3776109 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS044_RS18405 3776218..3777348 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS044_RS18410 3777437..3779353 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS044_RS18415 3779728..3780132 + 405 WP_000833521.1 DUF2541 family protein -
PS044_RS18420 3780159..3780872 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271507 WP_000809168.1 NZ_CP117580:3775957-3776109 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271507 NZ_CP117580:c3775908-3775851 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References