Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1091396..1091642 Replicon chromosome
Accession NZ_CP117580
Organism Escherichia albertii strain BIA_47

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag PS044_RS05245 Protein ID WP_000956458.1
Coordinates 1091490..1091642 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1091396..1091448 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS044_RS05230 1086800..1088599 + 1800 WP_273808277.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
PS044_RS05235 1088599..1090311 + 1713 WP_208629640.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS044_RS05240 1090491..1091225 + 735 WP_025238482.1 phosphoadenosine phosphosulfate reductase -
- 1091396..1091448 - 53 - - Antitoxin
PS044_RS05245 1091490..1091642 + 153 WP_000956458.1 Hok/Gef family protein Toxin
PS044_RS05250 1091768..1092805 - 1038 WP_059225076.1 alkaline phosphatase isozyme conversion aminopeptidase -
PS044_RS05255 1093058..1093966 + 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
PS044_RS05260 1093968..1095395 + 1428 WP_273808279.1 sulfate adenylyltransferase subunit CysN -
PS044_RS05265 1095395..1096000 + 606 WP_024164730.1 adenylyl-sulfate kinase -
PS044_RS05270 1096050..1096373 + 324 WP_001246114.1 DUF3561 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T271498 WP_000956458.1 NZ_CP117580:1091490-1091642 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT271498 NZ_CP117580:c1091448-1091396 [Escherichia albertii]
TTAGGTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References