Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3857829..3858087 Replicon chromosome
Accession NZ_CP117575
Organism Escherichia albertii strain BIA_5

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS037_RS18650 Protein ID WP_000809168.1
Coordinates 3857829..3857981 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3858030..3858087 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS037_RS18630 3853067..3853780 - 714 WP_001102345.1 acidic protein MsyB -
PS037_RS18635 3853807..3854211 - 405 WP_000833521.1 DUF2541 family protein -
PS037_RS18640 3854586..3856502 + 1917 WP_000516135.1 molecular chaperone DnaK -
PS037_RS18645 3856591..3857721 + 1131 WP_001118445.1 molecular chaperone DnaJ -
PS037_RS18650 3857829..3857981 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3858030..3858087 + 58 - - Antitoxin
PS037_RS18655 3858603..3859364 + 762 WP_059273362.1 outer membrane protein OmpK -
PS037_RS18660 3859385..3860878 + 1494 WP_059214855.1 sulfatase-like hydrolase/transferase -
PS037_RS18665 3861032..3862279 + 1248 WP_273821284.1 cytoplasmic protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271489 WP_000809168.1 NZ_CP117575:c3857981-3857829 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271489 NZ_CP117575:3858030-3858087 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References