Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1885364..1885610 Replicon chromosome
Accession NZ_CP117575
Organism Escherichia albertii strain BIA_5

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag PS037_RS09190 Protein ID WP_000956458.1
Coordinates 1885364..1885516 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1885558..1885610 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS037_RS09180 1881149..1883806 - 2658 WP_273821801.1 CRISPR-associated helicase Cas3' -
PS037_RS09185 1884059..1885171 + 1113 WP_085456548.1 IS4 family transposase -
PS037_RS09190 1885364..1885516 - 153 WP_000956458.1 Hok/Gef family protein Toxin
- 1885558..1885610 + 53 - - Antitoxin
PS037_RS09195 1885781..1886515 - 735 WP_001125130.1 phosphoadenosine phosphosulfate reductase -
PS037_RS09200 1886600..1888312 - 1713 WP_273821802.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS037_RS09205 1888312..1890111 - 1800 WP_273821803.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T271478 WP_000956458.1 NZ_CP117575:c1885516-1885364 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT271478 NZ_CP117575:1885558-1885610 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References