Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symER/SymE(toxin)
Location 3968343..3968755 Replicon chromosome
Accession NZ_CP117570
Organism Escherichia albertii strain BIA_50

Toxin (Protein)


Gene name symE Uniprot ID A0A8D9PK47
Locus tag PS035_RS19145 Protein ID WP_000132619.1
Coordinates 3968414..3968755 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name symR
Locus tag -
Coordinates 3968343..3968419 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS035_RS19135 (3965244) 3965244..3966833 + 1590 WP_157704341.1 type I restriction-modification system methyltransferase -
PS035_RS19140 (3966830) 3966830..3968185 + 1356 WP_161537581.1 restriction endonuclease subunit S -
- (3968343) 3968343..3968419 - 77 NuclAT_6 - Antitoxin
- (3968343) 3968343..3968419 - 77 NuclAT_6 - Antitoxin
- (3968343) 3968343..3968419 - 77 NuclAT_6 - Antitoxin
- (3968343) 3968343..3968419 - 77 NuclAT_6 - Antitoxin
- (3968343) 3968343..3968419 - 77 NuclAT_7 - Antitoxin
- (3968343) 3968343..3968419 - 77 NuclAT_7 - Antitoxin
- (3968343) 3968343..3968419 - 77 NuclAT_7 - Antitoxin
- (3968343) 3968343..3968419 - 77 NuclAT_7 - Antitoxin
PS035_RS19145 (3968414) 3968414..3968755 + 342 WP_000132619.1 endoribonuclease SymE Toxin
PS035_RS19150 (3968917) 3968917..3970296 + 1380 WP_059217670.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
PS035_RS19155 (3970296) 3970296..3971342 + 1047 WP_273817450.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
PS035_RS19160 (3971398) 3971398..3972476 - 1079 Protein_3748 DUF1998 domain-containing protein -
PS035_RS19165 (3972793) 3972793..3973724 - 932 Protein_3749 Rpn family recombination-promoting nuclease/putative transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12322.13 Da        Isoelectric Point: 7.8219

>T271459 WP_000132619.1 NZ_CP117570:3968414-3968755 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271459 NZ_CP117570:c3968419-3968343 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References