Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3891415..3891673 Replicon chromosome
Accession NZ_CP117570
Organism Escherichia albertii strain BIA_50

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS035_RS18775 Protein ID WP_000809168.1
Coordinates 3891521..3891673 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3891415..3891472 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS035_RS18760 3887222..3888469 - 1248 WP_059227922.1 hypothetical protein -
PS035_RS18765 3888623..3890116 - 1494 WP_059216552.1 sulfatase-like hydrolase/transferase -
PS035_RS18770 3890137..3890898 - 762 WP_059216553.1 outer membrane protein OmpK -
- 3891415..3891472 - 58 - - Antitoxin
PS035_RS18775 3891521..3891673 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS035_RS18780 3891777..3892907 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS035_RS18785 3892996..3894912 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS035_RS18790 3895287..3895691 + 405 WP_000833521.1 DUF2541 family protein -
PS035_RS18795 3895718..3896431 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271458 WP_000809168.1 NZ_CP117570:3891521-3891673 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271458 NZ_CP117570:c3891472-3891415 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References