Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3758244..3758502 Replicon chromosome
Accession NZ_CP117568
Organism Escherichia albertii strain BIA_5-2

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS053_RS18220 Protein ID WP_000809168.1
Coordinates 3758244..3758396 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3758445..3758502 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS053_RS18200 3753482..3754195 - 714 WP_001102345.1 acidic protein MsyB -
PS053_RS18205 3754222..3754626 - 405 WP_000833521.1 DUF2541 family protein -
PS053_RS18210 3755001..3756917 + 1917 WP_000516135.1 molecular chaperone DnaK -
PS053_RS18215 3757006..3758136 + 1131 WP_001118445.1 molecular chaperone DnaJ -
PS053_RS18220 3758244..3758396 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3758445..3758502 + 58 - - Antitoxin
PS053_RS18225 3759018..3759779 + 762 WP_105198098.1 outer membrane protein OmpK -
PS053_RS18230 3759800..3761293 + 1494 WP_059214855.1 sulfatase-like hydrolase/transferase -
PS053_RS18235 3761447..3762694 + 1248 WP_059224806.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271444 WP_000809168.1 NZ_CP117568:c3758396-3758244 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271444 NZ_CP117568:3758445-3758502 [Escherichia albertii]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References