Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-OrzO/SymE(toxin)
Location 3683450..3683862 Replicon chromosome
Accession NZ_CP117568
Organism Escherichia albertii strain BIA_5-2

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag PS053_RS17860 Protein ID WP_256878708.1
Coordinates 3683450..3683791 (-) Length 114 a.a.

Antitoxin (RNA)


Gene name OrzO
Locus tag -
Coordinates 3683786..3683862 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS053_RS17840 (3679824) 3679824..3680756 + 933 WP_256878710.1 Rpn family recombination-promoting nuclease/putative transposase -
PS053_RS17845 (3680909) 3680909..3681082 - 174 Protein_3479 GntR family transcriptional regulator -
PS053_RS17850 (3681307) 3681307..3682183 + 877 Protein_3480 DUF262 domain-containing protein -
PS053_RS17855 (3682237) 3682237..3683403 + 1167 WP_256878709.1 DUF1524 domain-containing protein -
PS053_RS17860 (3683450) 3683450..3683791 - 342 WP_256878708.1 endoribonuclease SymE Toxin
- (3683786) 3683786..3683862 + 77 NuclAT_10 - Antitoxin
- (3683786) 3683786..3683862 + 77 NuclAT_10 - Antitoxin
- (3683786) 3683786..3683862 + 77 NuclAT_10 - Antitoxin
- (3683786) 3683786..3683862 + 77 NuclAT_10 - Antitoxin
- (3683786) 3683786..3683862 + 77 NuclAT_9 - Antitoxin
- (3683786) 3683786..3683862 + 77 NuclAT_9 - Antitoxin
- (3683786) 3683786..3683862 + 77 NuclAT_9 - Antitoxin
- (3683786) 3683786..3683862 + 77 NuclAT_9 - Antitoxin
PS053_RS17865 (3684019) 3684019..3685374 - 1356 WP_256878707.1 restriction endonuclease subunit S -
PS053_RS17870 (3685371) 3685371..3686960 - 1590 WP_059250861.1 type I restriction-modification system methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12414.27 Da        Isoelectric Point: 8.4921

>T271440 WP_256878708.1 NZ_CP117568:c3683791-3683450 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRKLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTTQPPATEESE
LMQSLRQVCKLSARKQKQVQEFIGVITGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT271440 NZ_CP117568:3683786-3683862 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References