Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1856634..1856879 Replicon chromosome
Accession NZ_CP117568
Organism Escherichia albertii strain BIA_5-2

Toxin (Protein)


Gene name hokX Uniprot ID L4J2K8
Locus tag PS053_RS09085 Protein ID WP_000956460.1
Coordinates 1856634..1856786 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1856831..1856879 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS053_RS09060 1851902..1852225 - 324 WP_001246114.1 DUF3561 family protein -
PS053_RS09065 1852275..1852880 - 606 WP_256878896.1 adenylyl-sulfate kinase -
PS053_RS09070 1852880..1854307 - 1428 WP_054412002.1 sulfate adenylyltransferase subunit CysN -
PS053_RS09075 1854309..1855217 - 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
PS053_RS09080 1855471..1856508 + 1038 WP_256878880.1 alkaline phosphatase isozyme conversion aminopeptidase -
PS053_RS09085 1856634..1856786 - 153 WP_000956460.1 Hok/Gef family protein Toxin
- 1856831..1856879 + 49 - - Antitoxin
PS053_RS09090 1857050..1857784 - 735 WP_059216810.1 phosphoadenosine phosphosulfate reductase -
PS053_RS09095 1857964..1859676 - 1713 WP_273774864.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS053_RS09100 1859676..1861475 - 1800 WP_256878879.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5602.81 Da        Isoelectric Point: 7.7899

>T271432 WP_000956460.1 NZ_CP117568:c1856786-1856634 [Escherichia albertii]
MLTKYALVAIIVLCFTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 49 bp

>AT271432 NZ_CP117568:1856831-1856879 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829G7J5

Antitoxin

Download structure file

References