Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) hok-sok/-
Location 2287934..2288179 Replicon chromosome
Accession NZ_CP117562
Organism Escherichia albertii strain BIA_7

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag PS049_RS10985 Protein ID WP_000956458.1
Coordinates 2288027..2288179 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 2287934..2287982 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS049_RS10970 2283338..2285137 + 1800 WP_273783088.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
PS049_RS10975 2285137..2286849 + 1713 WP_001290735.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
PS049_RS10980 2287029..2287763 + 735 WP_001125131.1 phosphoadenosine phosphosulfate reductase -
- 2287934..2287982 - 49 - - Antitoxin
PS049_RS10985 2288027..2288179 + 153 WP_000956458.1 Hok/Gef family protein Toxin
PS049_RS10990 2288372..2289484 - 1113 WP_273783089.1 IS4 family transposase -
PS049_RS10995 2289737..2292394 + 2658 WP_273820300.1 CRISPR-associated helicase Cas3' -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-46)


Sequences


Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T271403 WP_000956458.1 NZ_CP117562:2288027-2288179 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp


Antitoxin


Download         Length: 49 bp

>AT271403 NZ_CP117562:c2287982-2287934 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83


Antitoxin

Download structure file

References