Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-sokW/SymE(toxin)
Location 480154..480567 Replicon chromosome
Accession NZ_CP117562
Organism Escherichia albertii strain BIA_7

Toxin (Protein)


Gene name symE Uniprot ID A0A8D9PK47
Locus tag PS049_RS02350 Protein ID WP_000132619.1
Coordinates 480226..480567 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name sokW
Locus tag -
Coordinates 480154..480231 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS049_RS02340 (477056) 477056..478645 + 1590 WP_059216569.1 type I restriction-modification system methyltransferase -
PS049_RS02345 (478642) 478642..479997 + 1356 WP_059216570.1 restriction endonuclease subunit S -
- (480154) 480154..480231 - 78 NuclAT_10 - Antitoxin
- (480154) 480154..480231 - 78 NuclAT_10 - Antitoxin
- (480154) 480154..480231 - 78 NuclAT_10 - Antitoxin
- (480154) 480154..480231 - 78 NuclAT_10 - Antitoxin
- (480154) 480154..480231 - 78 NuclAT_9 - Antitoxin
- (480154) 480154..480231 - 78 NuclAT_9 - Antitoxin
- (480154) 480154..480231 - 78 NuclAT_9 - Antitoxin
- (480154) 480154..480231 - 78 NuclAT_9 - Antitoxin
PS049_RS02350 (480226) 480226..480567 + 342 WP_000132619.1 endoribonuclease SymE Toxin
PS049_RS02355 (480729) 480729..482108 + 1380 WP_273820056.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
PS049_RS02360 (482108) 482108..483154 + 1047 WP_015953744.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
PS049_RS02365 (483210) 483210..484288 - 1079 Protein_461 DUF1998 domain-containing protein -
PS049_RS02370 (484603) 484603..485535 - 933 WP_273782440.1 Rpn family recombination-promoting nuclease/putative transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12322.13 Da        Isoelectric Point: 7.8219

>T271390 WP_000132619.1 NZ_CP117562:480226-480567 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 78 bp

>AT271390 NZ_CP117562:c480231-480154 [Escherichia albertii]
AGTCATAACTGCTATTCCTTGGAAAATAGTGATTGTGATGATCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References