Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 402100..402358 Replicon chromosome
Accession NZ_CP117562
Organism Escherichia albertii strain BIA_7

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS049_RS01975 Protein ID WP_000809168.1
Coordinates 402206..402358 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 402100..402157 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS049_RS01960 397908..399155 - 1248 WP_273782426.1 cytoplasmic protein -
PS049_RS01965 399309..400802 - 1494 WP_273820049.1 sulfatase-like hydrolase/transferase -
PS049_RS01970 400823..401584 - 762 WP_105198098.1 outer membrane protein OmpK -
- 402100..402157 - 58 - - Antitoxin
PS049_RS01975 402206..402358 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS049_RS01980 402462..403592 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS049_RS01985 403681..405597 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS049_RS01990 405972..406376 + 405 WP_273782428.1 DUF2541 family protein -
PS049_RS01995 406403..407116 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271389 WP_000809168.1 NZ_CP117562:402206-402358 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271389 NZ_CP117562:c402157-402100 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References