Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3941905..3942163 Replicon chromosome
Accession NZ_CP117558
Organism Escherichia albertii strain BIA_8

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS052_RS19500 Protein ID WP_000809168.1
Coordinates 3942011..3942163 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3941905..3941962 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS052_RS19485 3937712..3938959 - 1248 WP_059214856.1 hypothetical protein -
PS052_RS19490 3939113..3940606 - 1494 WP_103053229.1 sulfatase-like hydrolase/transferase -
PS052_RS19495 3940627..3941388 - 762 WP_001276206.1 outer membrane protein OmpK -
- 3941905..3941962 - 58 - - Antitoxin
PS052_RS19500 3942011..3942163 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS052_RS19505 3942271..3943401 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS052_RS19510 3943490..3945406 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS052_RS19515 3945781..3946185 + 405 WP_000833521.1 DUF2541 family protein -
PS052_RS19520 3946212..3946925 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271376 WP_000809168.1 NZ_CP117558:3942011-3942163 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271376 NZ_CP117558:c3941962-3941905 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References