Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 576164..576963 Replicon chromosome
Accession NZ_CP117558
Organism Escherichia albertii strain BIA_8

Toxin (Protein)


Gene name yhaV Uniprot ID A0A8H9C2I0
Locus tag PS052_RS02895 Protein ID WP_059227548.1
Coordinates 576164..576628 (-) Length 155 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag PS052_RS02900 Protein ID WP_103053959.1
Coordinates 576628..576963 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS052_RS02865 (571165) 571165..571599 - 435 WP_000948824.1 PTS galactosamine/N-acetylgalactosamine transporter subunit IIA -
PS052_RS02870 (571617) 571617..572495 - 879 WP_001295548.1 PTS N-acetylgalactosamine transporter subunit IID -
PS052_RS02875 (572485) 572485..573264 - 780 WP_000406226.1 PTS N-acetylgalactosamine transporter subunit IIC -
PS052_RS02880 (573275) 573275..573748 - 474 WP_002461030.1 PTS N-acetylgalactosamine transporter subunit IIB -
PS052_RS02885 (573771) 573771..575051 - 1281 WP_059227551.1 tagatose-bisphosphate aldolase subunit KbaZ -
PS052_RS02890 (575300) 575300..576109 + 810 WP_103053960.1 aga operon transcriptional regulator AgaR -
PS052_RS02895 (576164) 576164..576628 - 465 WP_059227548.1 type II toxin-antitoxin system ribonuclease toxin YhaV Toxin
PS052_RS02900 (576628) 576628..576963 - 336 WP_103053959.1 type II toxin-antitoxin system antitoxin PrlF Antitoxin
PS052_RS02905 (577112) 577112..578683 - 1572 WP_103053958.1 galactarate dehydratase -
PS052_RS02910 (579054) 579054..580388 + 1335 WP_025238277.1 galactarate/glucarate/glycerate transporter GarP -
PS052_RS02915 (580404) 580404..581174 + 771 WP_059235438.1 2-dehydro-3-deoxyglucarate aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(14-110)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 17819.26 Da        Isoelectric Point: 9.7301

>T271364 WP_059227548.1 NZ_CP117558:c576628-576164 [Escherichia albertii]
MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKN
KDWSRVKFGAGRFRLFFRYSEKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTQETEEKH

Download         Length: 465 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12336.89 Da        Isoelectric Point: 4.5392

>AT271364 WP_103053959.1 NZ_CP117558:c576963-576628 [Escherichia albertii]
MPANARSNAVLTTESKVTIRGQTTIPAPVREALKLKPGLDSIHYEILPGGQVFMCRQGDEQEDHTMNAFLRFLDADIQNN
PQKTRPFDIQQGKKLVAGMDVNIDDEIGDDE

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References