Detailed information of TA system TA271361

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 149858..150115
• Replicon: chromosome
• Accession: NZ_CP117558
• Organism: Escherichia albertii strain BIA_8

Toxin (Protein)

• Gene name: hokA
• Uniprot ID: A0A8D9PLG9
• Locus tag: PS052_RS00710
• Protein ID: WP_069913754.1
• Coordinates: 149963..150115 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokA
Locus tag	-
Coordinates	149858..149906 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PS052_RS00690	145087..146082	-	996	WP_103054035.1	acyltransferase	-
PS052_RS00695	146255..146554	+	300	WP_000979961.1	YsaB family lipoprotein	-
PS052_RS00700	146650..147561	+	912	WP_001168544.1	glycine--tRNA ligase subunit alpha	-
PS052_RS00705	147571..149640	+	2070	WP_103054034.1	glycine--tRNA ligase subunit beta	-
-	149858..149906	-	49	-	-	Antitoxin
PS052_RS00710	149963..150115	+	153	WP_069913754.1	type I toxin-antitoxin system toxin HokA	Toxin
PS052_RS00715	150092..150163	-	72	WP_212734940.1	hypothetical protein	-
PS052_RS00720	150303..150515	-	213	WP_000014594.1	RNA chaperone/antiterminator CspA	-
PS052_RS00725	150798..151088	-	291	WP_000455794.1	HTH-type transcriptional regulator	-
PS052_RS00730	151511..152221	+	711	WP_002460072.1	DUF3053 domain-containing protein	-
PS052_RS00735	152274..153248	-	975	WP_000804993.1	glyoxylate/hydroxypyruvate reductase GhrB	-
PS052_RS00740	153352..154011	-	660	WP_000747625.1	OmpA family lipoprotein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (5-46)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5940.19 Da
• Isoelectric Point: 7.7173

>T271361 WP_069913754.1 NZ_CP117558:149963-150115 [Escherichia albertii]
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAVFLACNLKE

Nucleotide

• Length: 153 bp

Antitoxin

Nucleotide

• Length: 49 bp

>AT271361 NZ_CP117558:c149906-149858 [Escherichia albertii]
GCATAGAGGGGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Structures

Antitoxin