Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4277907..4278165 Replicon chromosome
Accession NZ_CP117556
Organism Escherichia albertii strain BIA_89-5

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag PS032_RS21500 Protein ID WP_000809168.1
Coordinates 4278013..4278165 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4277907..4277964 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS032_RS21485 4273715..4274962 - 1248 WP_059227922.1 hypothetical protein -
PS032_RS21490 4275116..4276609 - 1494 WP_137649571.1 sulfatase-like hydrolase/transferase -
PS032_RS21495 4276630..4277391 - 762 WP_001276205.1 outer membrane protein OmpK -
- 4277907..4277964 - 58 - - Antitoxin
PS032_RS21500 4278013..4278165 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
PS032_RS21505 4278269..4279399 - 1131 WP_001118445.1 molecular chaperone DnaJ -
PS032_RS21510 4279488..4281404 - 1917 WP_000516135.1 molecular chaperone DnaK -
PS032_RS21515 4281779..4282183 + 405 WP_000833520.1 DUF2541 family protein -
PS032_RS21520 4282210..4282923 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T271351 WP_000809168.1 NZ_CP117556:4278013-4278165 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT271351 NZ_CP117556:c4277964-4277907 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References