Detailed information of TA system TA271341

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 2356220..2356591
• Replicon: chromosome
• Accession: NZ_CP117556
• Organism: Escherichia albertii strain BIA_89-5

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: -
• Locus tag: PS032_RS11730
• Protein ID: WP_137650428.1
• Coordinates: 2356397..2356591 (-)
• Length: 65 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	2356220..2356398 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PS032_RS11700 (2351998)	2351998..2352171	+	174	WP_032275239.1	protein YnaL	-
PS032_RS11705 (2352201)	2352201..2353574	+	1374	WP_137650219.1	ATP-dependent RNA helicase DbpA	-
PS032_RS11710 (2353677)	2353677..2354612	-	936	WP_059228647.1	tRNA 2-thiocytidine(32) synthetase TtcA	-
PS032_RS11715 (2354664)	2354664..2355899	-	1236	WP_137653527.1	site-specific integrase	-
PS032_RS11720 (2355901)	2355901..2356116	-	216	WP_000079604.1	excisionase XisR	-
- (2356220)	2356220..2356398	+	179	NuclAT_0	-	Antitoxin
- (2356220)	2356220..2356398	+	179	NuclAT_0	-	Antitoxin
- (2356220)	2356220..2356398	+	179	NuclAT_0	-	Antitoxin
- (2356220)	2356220..2356398	+	179	NuclAT_0	-	Antitoxin
PS032_RS11725 (2356195)	2356195..2356404	-	210	WP_000276809.1	double-strand break reduction protein RcbA	-
PS032_RS11730 (2356397)	2356397..2356591	-	195	WP_137650428.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
PS032_RS11735 (2356648)	2356648..2357457	-	810	WP_000166319.1	recombination protein RecT	-
PS032_RS11740 (2357450)	2357450..2360083	-	2634	WP_137650429.1	exodeoxyribonuclease VIII	-
PS032_RS11745 (2360185)	2360185..2360460	-	276	WP_044805262.1	hypothetical protein	-
PS032_RS11750 (2360596)	2360596..2360817	-	222	WP_062898151.1	cell division protein FtsZ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2354664..2398461	43797

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-54)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 7094.98 Da
• Isoelectric Point: 8.9329

>T271341 WP_137650428.1 NZ_CP117556:c2356591-2356397 [Escherichia albertii]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCEYRTGYGGSEKEALERWNKRTTGNNNGGVHV

Nucleotide

• Length: 195 bp

Antitoxin

Nucleotide

• Length: 179 bp

>AT271341 NZ_CP117556:2356220-2356398 [Escherichia albertii]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT

Structures

Antitoxin