271284

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2797738..2798067 Replicon chromosome
Accession NZ_CP117508
Organism Enterococcus faecalis strain CQJXZ21-077

Toxin (Protein)


Gene name txpA Uniprot ID A0A3N3Z2N6
Locus tag PSC78_RS13685 Protein ID WP_073340360.1
Coordinates 2797738..2797878 (+) Length 47 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2798018..2798067 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSC78_RS13665 2792952..2793944 + 993 WP_002354765.1 biotin--[acetyl-CoA-carboxylase] ligase -
PSC78_RS13670 2794208..2794804 - 597 WP_002414968.1 lytic polysaccharide monooxygenase -
PSC78_RS13675 2795530..2797146 + 1617 WP_104681241.1 phosphatase PAP2/LCP family protein -
PSC78_RS13680 2797476..2797619 + 144 WP_002392818.1 type I toxin-antitoxin system toxin PepG1 -
PSC78_RS13685 2797738..2797878 + 141 WP_073340360.1 putative holin-like toxin Toxin
- 2798018..2798067 + 50 - - Antitoxin
PSC78_RS13690 2798069..2801065 - 2997 WP_002385134.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-46)


Sequences

Toxin        


Download         Length: 47 a.a.        Molecular weight: 5218.33 Da        Isoelectric Point: 10.3265

>T271284 WP_073340360.1 NZ_CP117508:2797738-2797878 [Enterococcus faecalis]
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 141 bp

Antitoxin


Download         Length: 50 bp

>AT271284 NZ_CP117508:2798018-2798067 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3N3Z2N6

Antitoxin

Download structure file

References