Detailed information of TA system TA271277

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2797476..2797736
• Replicon: chromosome
• Accession: NZ_CP117508
• Organism: Enterococcus faecalis strain CQJXZ21-077

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: PSC78_RS13680
• Protein ID: WP_002392818.1
• Coordinates: 2797476..2797619 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2797552..2797736 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSC78_RS13660	2792598..2792813	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
PSC78_RS13665	2792952..2793944	+	993	WP_002354765.1	biotin--[acetyl-CoA-carboxylase] ligase	-
PSC78_RS13670	2794208..2794804	-	597	WP_002414968.1	lytic polysaccharide monooxygenase	-
PSC78_RS13675	2795530..2797146	+	1617	WP_104681241.1	phosphatase PAP2/LCP family protein	-
PSC78_RS13680	2797476..2797619	+	144	WP_002392818.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	2797552..2797736	-	185	-	-	Antitoxin
PSC78_RS13685	2797738..2797878	+	141	WP_073340360.1	putative holin-like toxin	-
PSC78_RS13690	2798069..2801065	-	2997	WP_002385134.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5344.49 Da
• Isoelectric Point: 10.6323

>T271277 WP_002392818.1 NZ_CP117508:2797476-2797619 [Enterococcus faecalis]
MNVSTKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 185 bp

>AT271277 NZ_CP117508:c2797736-2797552 [Enterococcus faecalis]
TGCTACAATAGAGATGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin