Detailed information of TA system TA271273

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2647122..2647381
• Replicon: chromosome
• Accession: NZ_CP117508
• Organism: Enterococcus faecalis strain CQJXZ21-077

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: PSC78_RS13000
• Protein ID: WP_075551663.1
• Coordinates: 2647280..2647381 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2647122..2647331 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSC78_RS12970	2642372..2643325	-	954	WP_002354964.1	siderophore ABC transporter substrate-binding protein	-
PSC78_RS12975	2643364..2644119	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
PSC78_RS12980	2644116..2645081	-	966	WP_002354961.1	iron chelate uptake ABC transporter family permease subunit	-
PSC78_RS12985	2645078..2646025	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
PSC78_RS12990	2646210..2646662	+	453	WP_002354958.1	YueI family protein	-
PSC78_RS12995	2646847..2646948	-	102	WP_075551663.1	putative holin-like toxin	-
-	2647122..2647331	+	210	-	-	Antitoxin
PSC78_RS13000	2647280..2647381	-	102	WP_075551663.1	putative holin-like toxin	Toxin
PSC78_RS13005	2647571..2649841	-	2271	WP_002392683.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
PSC78_RS13010	2650012..2650512	+	501	WP_002354954.1	cysteine hydrolase family protein	-
PSC78_RS13015	2651059..2651955	+	897	WP_002354953.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T271273 WP_075551663.1 NZ_CP117508:c2647381-2647280 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT271273 NZ_CP117508:2647122-2647331 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin