Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2737041..2737377 Replicon chromosome
Accession NZ_CP117503
Organism Enterococcus faecalis strain CQJXZ21-076

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag PSC77_RS13160 Protein ID WP_002396786.1
Coordinates 2737041..2737184 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2737328..2737377 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSC77_RS13145 (2732757) 2732757..2733389 - 633 WP_002358972.1 RloB family protein -
PSC77_RS13150 (2733398) 2733398..2734693 - 1296 WP_002410675.1 ATP-binding protein -
PSC77_RS13155 (2735155) 2735155..2736771 + 1617 WP_002372620.1 phosphatase PAP2/LCP family protein -
PSC77_RS13160 (2737041) 2737041..2737184 + 144 WP_002396786.1 putative holin-like toxin Toxin
- (2737328) 2737328..2737377 + 50 NuclAT_8 - Antitoxin
- (2737116) 2737116..2737378 - 263 NuclAT_7 - -
PSC77_RS13165 (2737379) 2737379..2742070 - 4692 WP_250652880.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T271260 WP_002396786.1 NZ_CP117503:2737041-2737184 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 50 bp

>AT271260 NZ_CP117503:2737328-2737377 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References