Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-RelB |
Location | 364795..365333 | Replicon | chromosome |
Accession | NZ_CP117370 | ||
Organism | Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain RM054 |
Toxin (Protein)
Gene name | yafQ | Uniprot ID | M7RHM1 |
Locus tag | PQP97_RS01660 | Protein ID | WP_001526148.1 |
Coordinates | 365058..365333 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | M7RMV7 |
Locus tag | PQP97_RS01655 | Protein ID | WP_000729713.1 |
Coordinates | 364795..365055 (+) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PQP97_RS01635 (360348) | 360348..361901 | + | 1554 | WP_000013007.1 | TROVE domain-containing protein | - |
PQP97_RS01640 (361910) | 361910..362101 | + | 192 | Protein_324 | TROVE domain-containing protein | - |
PQP97_RS01645 (362449) | 362449..363663 | + | 1215 | WP_001105521.1 | RNA-splicing ligase RtcB | - |
PQP97_RS01650 (363667) | 363667..364686 | + | 1020 | WP_000101027.1 | RNA 3'-terminal phosphate cyclase | - |
PQP97_RS01655 (364795) | 364795..365055 | + | 261 | WP_000729713.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
PQP97_RS01660 (365058) | 365058..365333 | + | 276 | WP_001526148.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
PQP97_RS01665 (365421) | 365421..368126 | - | 2706 | WP_000907029.1 | HTH-type transcriptional regulator MalT | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10739.34 Da Isoelectric Point: 8.8652
>T270869 WP_001526148.1 NZ_CP117370:365058-365333 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
MGQREIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDHPLQGSYSGYRDAHIEPDWILIYKITDECLR
FERTGTHADLF
MGQREIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDHPLQGSYSGYRDAHIEPDWILIYKITDECLR
FERTGTHADLF
Download Length: 276 bp
Antitoxin
Download Length: 87 a.a. Molecular weight: 9446.80 Da Isoelectric Point: 4.4734
>AT270869 WP_000729713.1 NZ_CP117370:364795-365055 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
MAANALVRARIDETLKDQAADVLAEMGLTISDLIRITLTKVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI
MAANALVRARIDETLKDQAADVLAEMGLTISDLIRITLTKVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI
Download Length: 261 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3V4SM83 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4D6P2L2 |