Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 383336..383874 Replicon chromosome
Accession NZ_CP117348
Organism Salmonella enterica subsp. enterica serovar Heidelberg strain RM101

Toxin (Protein)


Gene name yafQ Uniprot ID A0A8E7RBX8
Locus tag PQQ11_RS01780 Protein ID WP_001682450.1
Coordinates 383599..383874 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A7U1KUN1
Locus tag PQQ11_RS01775 Protein ID WP_000729714.1
Coordinates 383336..383596 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQQ11_RS01760 (379047) 379047..380600 + 1554 WP_000013007.1 TROVE domain-containing protein -
PQQ11_RS01765 (380948) 380948..382162 + 1215 WP_001105530.1 RNA-splicing ligase RtcB -
PQQ11_RS01770 (382166) 382166..383227 + 1062 WP_000101032.1 RNA 3'-terminal phosphate cyclase -
PQQ11_RS01775 (383336) 383336..383596 + 261 WP_000729714.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PQQ11_RS01780 (383599) 383599..383874 + 276 WP_001682450.1 type II toxin-antitoxin system YafQ family toxin Toxin
PQQ11_RS01785 (383962) 383962..386667 - 2706 WP_000907043.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10605.16 Da        Isoelectric Point: 8.9063

>T270696 WP_001682450.1 NZ_CP117348:383599-383874 [Salmonella enterica subsp. enterica serovar Heidelberg]
MGQREIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDHPLQGSYSGYRDAHIGPDWILVDKITDECLR
FERTGTHADLF

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9445.82 Da        Isoelectric Point: 4.6028

>AT270696 WP_000729714.1 NZ_CP117348:383336-383596 [Salmonella enterica subsp. enterica serovar Heidelberg]
MAANALVRARIDETLKNQAADVLAEMGLTISDLIRITLTKVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U1KUN1

References