Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 358003..358541 Replicon chromosome
Accession NZ_CP117346
Organism Salmonella enterica subsp. enterica serovar Dublin strain RM104

Toxin (Protein)


Gene name yafQ Uniprot ID M7RHM1
Locus tag PQP85_RS01625 Protein ID WP_001526148.1
Coordinates 358266..358541 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID M7RMV7
Locus tag PQP85_RS01620 Protein ID WP_000729713.1
Coordinates 358003..358263 (+) Length 87 a.a.

Genomic Context

PQP85_RS01605PQP85_RS01610PQP85_RS01615PQP85_RS01620PQP85_RS01625PQP85_RS01630
Location: 353764..355317 (1554 bp)
Type: Others
Protein ID: WP_000013013.1
Location: 355665..356879 (1215 bp)
Type: Others
Protein ID: WP_052895987.1
Location: 356883..357894 (1012 bp)
Type: Others
Protein ID: Protein_318
Location: 358003..358263 (261 bp)
Type: Antitoxin
Protein ID: WP_000729713.1
Location: 358266..358541 (276 bp)
Type: Toxin
Protein ID: WP_001526148.1
Location: 358629..361334 (2706 bp)
Type: Others
Protein ID: WP_000907030.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PQP85_RS01605 (353764)353764..355317+1554WP_000013013.1TROVE domain-containing protein-
PQP85_RS01610 (355665)355665..356879+1215WP_052895987.1RNA-splicing ligase RtcB-
PQP85_RS01615 (356883)356883..357894+1012Protein_318RNA 3'-terminal phosphate cyclase-
PQP85_RS01620 (358003)358003..358263+261WP_000729713.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
PQP85_RS01625 (358266)358266..358541+276WP_001526148.1type II toxin-antitoxin system YafQ family toxinToxin
PQP85_RS01630 (358629)358629..361334-2706WP_000907030.1HTH-type transcriptional regulator MalT-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10739.34 Da        Isoelectric Point: 8.8652

>T270674 WP_001526148.1 NZ_CP117346:358266-358541 [Salmonella enterica subsp. enterica serovar Dublin]
MGQREIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDHPLQGSYSGYRDAHIEPDWILIYKITDECLR
FERTGTHADLF

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9446.80 Da        Isoelectric Point: 4.4734

>AT270674 WP_000729713.1 NZ_CP117346:358003-358263 [Salmonella enterica subsp. enterica serovar Dublin]
MAANALVRARIDETLKDQAADVLAEMGLTISDLIRITLTKVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A3V4SM83

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A4D6P2L2

References