270523

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 364530..365068 Replicon chromosome
Accession NZ_CP117327
Organism Salmonella enterica subsp. enterica serovar Saintpaul strain RM106

Toxin (Protein)


Gene name yafQ Uniprot ID A0A7U1Q7V6
Locus tag PQP95_RS01665 Protein ID WP_001521736.1
Coordinates 364793..365068 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A5V2G724
Locus tag PQP95_RS01660 Protein ID WP_000729830.1
Coordinates 364530..364790 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQP95_RS01645 (360285) 360285..361838 + 1554 WP_000013017.1 TROVE domain-containing protein -
PQP95_RS01650 (362184) 362184..363398 + 1215 WP_023137705.1 RNA-splicing ligase RtcB -
PQP95_RS01655 (363402) 363402..364421 + 1020 WP_000101027.1 RNA 3'-terminal phosphate cyclase -
PQP95_RS01660 (364530) 364530..364790 + 261 WP_000729830.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PQP95_RS01665 (364793) 364793..365068 + 276 WP_001521736.1 type II toxin-antitoxin system YafQ family toxin Toxin
PQP95_RS01670 (365156) 365156..367861 - 2706 WP_274891280.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-84)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10618.25 Da        Isoelectric Point: 9.7714

>T270523 WP_001521736.1 NZ_CP117327:364793-365068 [Salmonella enterica subsp. enterica serovar Saintpaul]
MGQRKIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDHPLQGSYSGYRDAHIGPDWILIDKITDECLR
FERTGTHADLF

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9473.87 Da        Isoelectric Point: 4.6028

>AT270523 WP_000729830.1 NZ_CP117327:364530-364790 [Salmonella enterica subsp. enterica serovar Saintpaul]
MAANVLVRARIDETLKNQAADVLAEMGLTISDLIRITLTKVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U1Q7V6

Antitoxin

Source ID Structure
AlphaFold DB A0A5V2G724

References