Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 288787..289300 Replicon chromosome
Accession NZ_CP117288
Organism Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MGCS35957_RS01550 Protein ID WP_084916229.1
Coordinates 288787..289041 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MGCS35957_RS01555 Protein ID WP_003053797.1
Coordinates 289034..289300 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MGCS35957_RS01520 (MGCS35957_00622) 285029..285439 - 411 WP_003053802.1 conjugal transfer protein -
MGCS35957_RS01525 (MGCS35957_00624) 285442..285666 - 225 WP_003053785.1 hypothetical protein -
MGCS35957_RS01530 (MGCS35957_00626) 285670..286680 - 1011 WP_022554213.1 conjugal transfer protein -
MGCS35957_RS01535 (MGCS35957_00628) 286692..287228 - 537 WP_003053800.1 hypothetical protein -
MGCS35957_RS01540 (MGCS35957_00630) 287255..287485 - 231 WP_003053793.1 hypothetical protein -
MGCS35957_RS01545 (MGCS35957_00632) 287505..288731 - 1227 WP_084916231.1 replication initiation factor domain-containing protein -
MGCS35957_RS01550 (MGCS35957_00634) 288787..289041 - 255 WP_084916229.1 Txe/YoeB family addiction module toxin Toxin
MGCS35957_RS01555 (MGCS35957_00636) 289034..289300 - 267 WP_003053797.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MGCS35957_RS01560 (MGCS35957_00638) 289565..291250 - 1686 WP_084916228.1 FtsK/SpoIIIE domain-containing protein -
MGCS35957_RS01565 (MGCS35957_00640) 291267..291728 - 462 WP_003056467.1 hypothetical protein -
MGCS35957_RS01570 (MGCS35957_00642) 291747..292043 - 297 WP_003056470.1 hypothetical protein -
MGCS35957_RS01575 (MGCS35957_00644) 292083..292328 - 246 WP_003056472.1 hypothetical protein -
MGCS35957_RS01580 (MGCS35957_00646) 292901..293242 + 342 WP_110408064.1 helix-turn-helix transcriptional regulator -
MGCS35957_RS01585 (MGCS35957_00648) 293446..293751 + 306 WP_014612001.1 hypothetical protein -
MGCS35957_RS01590 (MGCS35957_00650) 293786..294145 - 360 WP_003053656.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10502.78 Da        Isoelectric Point: 8.4060

>T270234 WP_084916229.1 NZ_CP117288:c289041-288787 [Streptococcus dysgalactiae subsp. equisimilis]
MFNFTEEAWEDYTSWQREDKKNLKRINRLIEDIKRHPFEGIGKPEPLKYRYSGAWSRRITDEHRLVYTVEQNDIYFLSFR
DHYK

Download         Length: 255 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10402.81 Da        Isoelectric Point: 4.5216

>AT270234 WP_003053797.1 NZ_CP117288:c289300-289034 [Streptococcus dysgalactiae subsp. equisimilis]
MEAVVYSNFRNNLKDYMKKVNDEYEPLMVVNKNPEENIVVLSKDNWDSIQETIRIMNNEYLSDKVLSGLEQVKQKKVTQH
QLLEVEDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References