270231

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 296023..296536 Replicon chromosome
Accession NZ_CP117287
Organism Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MGCS36044_RS01635 Protein ID WP_084916229.1
Coordinates 296023..296277 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MGCS36044_RS01640 Protein ID WP_003053797.1
Coordinates 296270..296536 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MGCS36044_RS01605 (MGCS36044_00644) 292265..292675 - 411 WP_003053802.1 conjugal transfer protein -
MGCS36044_RS01610 (MGCS36044_00646) 292678..292902 - 225 WP_003053785.1 hypothetical protein -
MGCS36044_RS01615 (MGCS36044_00648) 292906..293916 - 1011 WP_022554213.1 conjugal transfer protein -
MGCS36044_RS01620 (MGCS36044_00650) 293928..294464 - 537 WP_003053800.1 hypothetical protein -
MGCS36044_RS01625 (MGCS36044_00652) 294491..294721 - 231 WP_003053793.1 hypothetical protein -
MGCS36044_RS01630 (MGCS36044_00654) 294741..295967 - 1227 WP_084916231.1 replication initiation factor domain-containing protein -
MGCS36044_RS01635 (MGCS36044_00656) 296023..296277 - 255 WP_084916229.1 Txe/YoeB family addiction module toxin Toxin
MGCS36044_RS01640 (MGCS36044_00658) 296270..296536 - 267 WP_003053797.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MGCS36044_RS01645 (MGCS36044_00660) 296801..298486 - 1686 WP_084916228.1 FtsK/SpoIIIE domain-containing protein -
MGCS36044_RS01650 (MGCS36044_00662) 298503..298964 - 462 WP_003056467.1 hypothetical protein -
MGCS36044_RS01655 (MGCS36044_00664) 298983..299279 - 297 WP_003056470.1 hypothetical protein -
MGCS36044_RS01660 (MGCS36044_00666) 299319..299564 - 246 WP_003056472.1 hypothetical protein -
MGCS36044_RS01665 (MGCS36044_00668) 300137..300478 + 342 WP_110408064.1 helix-turn-helix transcriptional regulator -
MGCS36044_RS01670 (MGCS36044_00670) 300682..300987 + 306 WP_014612001.1 hypothetical protein -
MGCS36044_RS01675 (MGCS36044_00672) 301022..301381 - 360 WP_275902592.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 271531..303460 31929


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10502.78 Da        Isoelectric Point: 8.4060

>T270231 WP_084916229.1 NZ_CP117287:c296277-296023 [Streptococcus dysgalactiae subsp. equisimilis]
MFNFTEEAWEDYTSWQREDKKNLKRINRLIEDIKRHPFEGIGKPEPLKYRYSGAWSRRITDEHRLVYTVEQNDIYFLSFR
DHYK

Download         Length: 255 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10402.81 Da        Isoelectric Point: 4.5216

>AT270231 WP_003053797.1 NZ_CP117287:c296536-296270 [Streptococcus dysgalactiae subsp. equisimilis]
MEAVVYSNFRNNLKDYMKKVNDEYEPLMVVNKNPEENIVVLSKDNWDSIQETIRIMNNEYLSDKVLSGLEQVKQKKVTQH
QLLEVEDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References