270205

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 404238..404829 Replicon chromosome
Accession NZ_CP117261
Organism Rhizobium tumorigenes strain 932

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PR016_RS01975 Protein ID WP_278331359.1
Coordinates 404238..404522 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag PR016_RS01980 Protein ID WP_278331360.1
Coordinates 404533..404829 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PR016_RS01960 (PR016_01960) 400231..400782 + 552 WP_278331356.1 LemA family protein -
PR016_RS01965 (PR016_01965) 400878..402152 + 1275 WP_278331357.1 3-phosphoshikimate 1-carboxyvinyltransferase -
PR016_RS01970 (PR016_01970) 402201..404135 + 1935 WP_278331358.1 DUF2207 domain-containing protein -
PR016_RS01975 (PR016_01975) 404238..404522 + 285 WP_278331359.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PR016_RS01980 (PR016_01980) 404533..404829 + 297 WP_278331360.1 HigA family addiction module antitoxin Antitoxin
PR016_RS01985 (PR016_01985) 404935..407169 + 2235 WP_278331361.1 glycine--tRNA ligase subunit beta -
PR016_RS01990 (PR016_01990) 407227..407808 - 582 WP_278331363.1 histidine phosphatase family protein -
PR016_RS01995 (PR016_01995) 407978..409795 - 1818 WP_278331364.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(17-68)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10433.88 Da        Isoelectric Point: 7.2784

>T270205 WP_278331359.1 NZ_CP117261:404238-404522 [Rhizobium tumorigenes]
MAILSFKDGSTRAVASGAVPKGFPADLARRAIRKLTMIEFANQLSDLRSPPANHLEALKGDRAGQHSIRINDQWRICFVW
TDAGVEDVEIVDYH

Download         Length: 285 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11205.07 Da        Isoelectric Point: 6.7286

>AT270205 WP_278331360.1 NZ_CP117261:404533-404829 [Rhizobium tumorigenes]
MKHILPPVHPGEILREEYLAPLEMSAGALARKLNVPRTRIERLVAEETPVTIDTALRLARFFDTTPEFWMNMQTGYELKR
QAEEKRAEIAAIPVLHVA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References