Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2257153..2257370 Replicon chromosome
Accession NZ_CP117242
Organism Staphylococcus aureus strain ATCC 14458

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag PQQ25_RS11815 Protein ID WP_001802298.1
Coordinates 2257266..2257370 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2257153..2257208 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQQ25_RS11790 2253356..2254021 - 666 WP_001024094.1 SDR family oxidoreductase -
PQQ25_RS11795 2254173..2254493 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PQQ25_RS11800 2254495..2255475 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
PQQ25_RS11805 2255741..2256832 + 1092 WP_000495671.1 lytic regulatory protein -
- 2257153..2257208 + 56 - - Antitoxin
PQQ25_RS11815 2257266..2257370 - 105 WP_001802298.1 hypothetical protein Toxin
PQQ25_RS11820 2257531..2258014 - 484 Protein_2232 recombinase family protein -
PQQ25_RS11825 2258057..2259193 - 1137 WP_000115564.1 SAP domain-containing protein -
PQQ25_RS11830 2259482..2259574 + 93 WP_001790138.1 hypothetical protein -
PQQ25_RS11835 2260279..2261136 - 858 WP_033841791.1 HAD family hydrolase -
PQQ25_RS11840 2261204..2261986 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T270163 WP_001802298.1 NZ_CP117242:c2257370-2257266 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT270163 NZ_CP117242:2257153-2257208 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References