270152

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2404727..2404911 Replicon chromosome
Accession NZ_CP117238
Organism Staphylococcus aureus strain ATCC 23235

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag PQQ27_RS12085 Protein ID WP_000482652.1
Coordinates 2404804..2404911 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2404727..2404787 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQQ27_RS12070 (PQQ27_12070) 2400182..2400313 - 132 WP_223197975.1 hypothetical protein -
PQQ27_RS12075 (PQQ27_12075) 2400580..2402313 - 1734 WP_000486487.1 ABC transporter ATP-binding protein -
PQQ27_RS12080 (PQQ27_12080) 2402338..2404101 - 1764 WP_001064825.1 ABC transporter ATP-binding protein -
- 2404727..2404787 + 61 - - Antitoxin
PQQ27_RS12085 (PQQ27_12085) 2404804..2404911 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
PQQ27_RS12090 (PQQ27_12090) 2405045..2405431 - 387 WP_000779360.1 flippase GtxA -
PQQ27_RS12095 (PQQ27_12095) 2405699..2406841 + 1143 WP_001176863.1 glycerate kinase -
PQQ27_RS12100 (PQQ27_12100) 2406901..2407560 + 660 WP_000831298.1 membrane protein -
PQQ27_RS12105 (PQQ27_12105) 2407742..2408953 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
PQQ27_RS12110 (PQQ27_12110) 2409076..2409549 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T270152 WP_000482652.1 NZ_CP117238:c2404911-2404804 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT270152 NZ_CP117238:2404727-2404787 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References