Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2175657..2175854 Replicon chromosome
Accession NZ_CP117230
Organism Staphylococcus aureus strain ATCC 25923

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag PQQ26_RS10795 Protein ID WP_073392962.1
Coordinates 2175750..2175854 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2175657..2175695 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQQ26_RS10770 (PQQ26_10770) 2171832..2172497 - 666 WP_001024099.1 SDR family oxidoreductase -
PQQ26_RS10775 (PQQ26_10775) 2172649..2172969 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PQQ26_RS10780 (PQQ26_10780) 2172971..2173951 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
PQQ26_RS10785 (PQQ26_10785) 2174217..2175308 + 1092 WP_000495684.1 hypothetical protein -
PQQ26_RS10790 (PQQ26_10790) 2175637..2175711 + 75 Protein_2088 hypothetical protein -
- 2175657..2175695 + 39 - - Antitoxin
PQQ26_RS10795 (PQQ26_10795) 2175750..2175854 - 105 WP_073392962.1 hypothetical protein Toxin
PQQ26_RS10800 (PQQ26_10800) 2176534..2176692 + 159 WP_001792784.1 hypothetical protein -
PQQ26_RS10805 (PQQ26_10805) 2177351..2178208 - 858 WP_000370937.1 HAD family hydrolase -
PQQ26_RS10810 (PQQ26_10810) 2178276..2179058 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T270119 WP_073392962.1 NZ_CP117230:c2175854-2175750 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT270119 NZ_CP117230:2175657-2175695 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References