Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2462425..2462609 Replicon chromosome
Accession NZ_CP117203
Organism Staphylococcus aureus strain 2022QW-00133

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag PQQ74_RS12295 Protein ID WP_000482650.1
Coordinates 2462502..2462609 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2462425..2462485 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQQ74_RS12280 2457955..2458122 - 168 WP_001790576.1 hypothetical protein -
PQQ74_RS12285 2458353..2460086 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
PQQ74_RS12290 2460111..2461874 - 1764 WP_001064838.1 ABC transporter ATP-binding protein -
- 2462425..2462485 + 61 - - Antitoxin
PQQ74_RS12295 2462502..2462609 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
PQQ74_RS12300 2462743..2463129 - 387 WP_000779358.1 flippase GtxA -
PQQ74_RS12305 2463397..2464539 + 1143 WP_001176863.1 glycerate kinase -
PQQ74_RS12310 2464599..2465258 + 660 WP_000831298.1 membrane protein -
PQQ74_RS12315 2465440..2466651 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
PQQ74_RS12320 2466774..2467247 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T270091 WP_000482650.1 NZ_CP117203:c2462609-2462502 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT270091 NZ_CP117203:2462425-2462485 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References