Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2170812..2171029 Replicon chromosome
Accession NZ_CP117203
Organism Staphylococcus aureus strain 2022QW-00133

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag PQQ74_RS10770 Protein ID WP_001802298.1
Coordinates 2170925..2171029 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2170812..2170867 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQQ74_RS10745 2166949..2167614 - 666 WP_001024094.1 SDR family oxidoreductase -
PQQ74_RS10750 2167766..2168086 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PQQ74_RS10755 2168088..2169068 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
PQQ74_RS10760 2169334..2170425 + 1092 WP_000495671.1 lytic regulatory protein -
- 2170812..2170867 + 56 - - Antitoxin
PQQ74_RS10770 2170925..2171029 - 105 WP_001802298.1 hypothetical protein Toxin
PQQ74_RS10775 2171190..2171673 - 484 Protein_2081 recombinase family protein -
PQQ74_RS10780 2171716..2172852 - 1137 WP_000115564.1 SAP domain-containing protein -
PQQ74_RS10785 2173141..2173233 + 93 WP_001790138.1 hypothetical protein -
PQQ74_RS10790 2173938..2174795 - 858 WP_000370924.1 HAD family hydrolase -
PQQ74_RS10795 2174863..2175645 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T270089 WP_001802298.1 NZ_CP117203:c2171029-2170925 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT270089 NZ_CP117203:2170812-2170867 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References