Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 407127..407778 Replicon plasmid unnamed1
Accession NZ_CP117200
Organism Pantoea sp. SS70

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PO881_RS21515 Protein ID WP_137387145.1
Coordinates 407127..407471 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PO881_RS21520 Protein ID WP_280172933.1
Coordinates 407464..407778 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO881_RS21495 (PO881_21495) 402247..402945 + 699 WP_280172931.1 methionine ABC transporter permease -
PO881_RS21500 (PO881_21500) 402942..403817 + 876 WP_192414680.1 MetQ/NlpA family ABC transporter substrate-binding protein -
PO881_RS21505 (PO881_21505) 403995..405434 + 1440 WP_110867055.1 MFS transporter -
PO881_RS21510 (PO881_21510) 405431..406645 + 1215 WP_280172932.1 monooxygenase -
PO881_RS21515 (PO881_21515) 407127..407471 + 345 WP_137387145.1 toxin Toxin
PO881_RS21520 (PO881_21520) 407464..407778 + 315 WP_280172933.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PO881_RS21525 (PO881_21525) 407913..408860 - 948 WP_280172934.1 sulfonate ABC transporter substrate-binding protein -
PO881_RS21530 (PO881_21530) 409115..411172 + 2058 WP_280172935.1 FUSC family protein -
PO881_RS21535 (PO881_21535) 411188..411877 + 690 WP_222212286.1 aspartate/glutamate racemase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..779368 779368


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA/HigA-2

(20-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13492.32 Da        Isoelectric Point: 9.9070

>T270078 WP_137387145.1 NZ_CP117200:407127-407471 [Pantoea sp. SS70]
MHATFIELSSFQKYRVEYLSDDQFRLFQNMLMADPEKGDVIPDTGGLRKVRFRDERRNKGTRGGIRVIYYWTNEKGQFIL
FTIYDKDQRDDLTKQQRDALGSALNVIKKGLRHD

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12046.87 Da        Isoelectric Point: 10.1328

>AT270078 WP_280172933.1 NZ_CP117200:407464-407778 [Pantoea sp. SS70]
MTERDIFSELMTGMQELKHHKDGKITLKTYKVSKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRSRP
NAQAVLLIRMVQQNPETLKTLAQL

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References