Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 164172..165010 Replicon plasmid unnamed1
Accession NZ_CP117200
Organism Pantoea sp. SS70

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag PO881_RS20365 Protein ID WP_277975061.1
Coordinates 164172..164654 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag PO881_RS20370 Protein ID WP_277976470.1
Coordinates 164672..165010 (-) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO881_RS20345 (PO881_20345) 159459..160421 + 963 WP_280173324.1 ABC transporter substrate-binding protein -
PO881_RS20350 (PO881_20350) 160429..161844 + 1416 WP_280173194.1 amidohydrolase family protein -
PO881_RS20355 (PO881_20355) 161850..163370 - 1521 WP_277975059.1 MDR family MFS transporter -
PO881_RS20360 (PO881_20360) 163450..164115 + 666 WP_277975060.1 TetR/AcrR family transcriptional regulator -
PO881_RS20365 (PO881_20365) 164172..164654 - 483 WP_277975061.1 type II toxin-antitoxin system YhaV family toxin Toxin
PO881_RS20370 (PO881_20370) 164672..165010 - 339 WP_277976470.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
PO881_RS20375 (PO881_20375) 165226..165792 + 567 WP_110866778.1 peroxiredoxin -
PO881_RS20380 (PO881_20380) 165808..167037 + 1230 WP_280173196.1 thioredoxin family protein -
PO881_RS20385 (PO881_20385) 167055..167612 + 558 WP_192234665.1 sigma-70 family RNA polymerase sigma factor -
PO881_RS20390 (PO881_20390) 167599..168228 + 630 WP_280173197.1 NrsF family protein -
PO881_RS20395 (PO881_20395) 168389..168658 + 270 WP_101761698.1 DUF1471 family periplasmic protein YahO -
PO881_RS20400 (PO881_20400) 168826..169893 - 1068 WP_280173198.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..779368 779368


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(14-112)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 18802.44 Da        Isoelectric Point: 9.2890

>T270074 WP_277975061.1 NZ_CP117200:c164654-164172 [Pantoea sp. SS70]
VDYMEINGWKFYFHACFSAQVTSLAQEVLQLRVEKPHEYHKKKQTKLLAAIYKVVTEVIARDPLNPQFRQGGTLGDENRY
WFRAKFLQQFRLFFRCSEQSKTIILGWVNDFGTLRAYESKTDAYKTFKRMLDAGHPPSDWEQLLRESTGESGFLFQAPFS

Download         Length: 483 bp

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12523.10 Da        Isoelectric Point: 4.1760

>AT270074 WP_277976470.1 NZ_CP117200:c165010-164672 [Pantoea sp. SS70]
VFKFDLVDVSLRAESRLTERSQTTIPAAIRDALQLKPGEIIEYSLLSGGKVIMSKQNDEQDDPAVQHFLTFLERDMVSNP
QHIHSVPVEFWSGMENLVAGIDVDLDAPLTDD

Download         Length: 339 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References