269981

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2017258..2018606 Replicon chromosome
Accession NZ_CP117055
Organism Vibrio harveyi strain VH21FL

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag PQE20_RS25790 Protein ID WP_272760116.1
Coordinates 2017569..2018606 (+) Length 346 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag PQE20_RS25785 Protein ID WP_102249914.1
Coordinates 2017258..2017569 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQE20_RS25770 (PQE20_25770) 2013168..2014874 - 1707 WP_272760113.1 type I restriction-modification system subunit M -
PQE20_RS25775 (PQE20_25775) 2014951..2016681 - 1731 WP_272760114.1 N-6 DNA methylase -
PQE20_RS25780 (PQE20_25780) 2016959..2017273 + 315 WP_272760115.1 helix-turn-helix transcriptional regulator -
PQE20_RS25785 (PQE20_25785) 2017258..2017569 + 312 WP_102249914.1 HipA N-terminal domain-containing protein Antitoxin
PQE20_RS25790 (PQE20_25790) 2017569..2018606 + 1038 WP_272760116.1 HipA domain-containing protein Toxin
PQE20_RS25795 (PQE20_25795) 2018636..2019658 + 1023 WP_272760117.1 HipA domain-containing protein -
PQE20_RS25800 (PQE20_25800) 2020124..2021083 - 960 WP_272760118.1 HNH endonuclease signature motif containing protein -
PQE20_RS25805 (PQE20_25805) 2021086..2021601 - 516 Protein_1781 recombinase family protein -
PQE20_RS25810 (PQE20_25810) 2021972..2022463 + 492 WP_005428296.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(60-307)

Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 346 a.a.        Molecular weight: 40057.45 Da        Isoelectric Point: 5.3490

>T269981 WP_272760116.1 NZ_CP117055:2017569-2018606 [Vibrio harveyi]
MFPENKCLISLVALNDRNRFQDEYTKATVKDLTGDHTTTVRLPFTKNEFVSEQPKRQKGMSISGYQPKLSLVVNDNQFEV
VENEAQYILKPSPNEFPHLAENEHATMLVMKKLNFDIPKFGLTRFKKDNDGNEEKAFVIKRFDRNSDREAIHQEQLDAAM
DIAEKYGKTKDDDEGYVSYERVWKFLSQHVEDTLKLKQDFFRRIFTAYLLGNNDLHLRNFGILRPEVGPDTLAPIYDYVS
VAPYKDYITDQMALPLLELEEGGEKQTNGFATYSKYTGYDFIQFGSAIGLNPKMTEKLLDDILKKIPTILEIYKNSFVPE
KQYQAIEKWILSIEYYANKRDAFAP

Download         Length: 1038 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11960.61 Da        Isoelectric Point: 9.7807

>AT269981 WP_102249914.1 NZ_CP117055:2017258-2017569 [Vibrio harveyi]
MDRKVKVFLYNHLAGVLTQKNSTFTFTYDENYRGKPLSLSFPLAQKSFSQEQLHPFFASLAPEGWLKKRYSETQRIDEND
TLGMLIQNGKNLIGAVRIERFDN

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References