Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | ldrD-istR/Ldr(toxin) |
| Location | 1881386..1881607 | Replicon | chromosome |
| Accession | NZ_CP116981 | ||
| Organism | Escherichia coli strain E6474 | ||
Toxin (Protein)
| Gene name | ldrD | Uniprot ID | S1PGT3 |
| Locus tag | PO910_RS09100 | Protein ID | WP_000170954.1 |
| Coordinates | 1881386..1881493 (-) | Length | 36 a.a. |
Antitoxin (RNA)
| Gene name | istR | ||
| Locus tag | - | ||
| Coordinates | 1881541..1881607 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PO910_RS09075 (1877230) | 1877230..1878312 | + | 1083 | WP_000804726.1 | peptide chain release factor 1 | - |
| PO910_RS09080 (1878312) | 1878312..1879145 | + | 834 | WP_000456467.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| PO910_RS09085 (1879142) | 1879142..1879534 | + | 393 | WP_000200378.1 | invasion regulator SirB2 | - |
| PO910_RS09090 (1879538) | 1879538..1880347 | + | 810 | WP_001257044.1 | invasion regulator SirB1 | - |
| PO910_RS09095 (1880383) | 1880383..1881237 | + | 855 | WP_000811065.1 | 3-deoxy-8-phosphooctulonate synthase | - |
| PO910_RS09100 (1881386) | 1881386..1881493 | - | 108 | WP_000170954.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_34 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_34 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_34 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_34 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_37 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_37 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_37 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_37 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_40 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_40 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_40 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_40 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_43 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_43 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_43 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_43 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_46 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_46 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_46 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_46 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_49 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_49 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_49 | - | - |
| - (1881543) | 1881543..1881606 | + | 64 | NuclAT_49 | - | - |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_14 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_14 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_14 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_14 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_17 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_17 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_17 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_17 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_20 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_20 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_20 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_20 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_23 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_23 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_23 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_23 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_26 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_26 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_26 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_26 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_29 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_29 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_29 | - | Antitoxin |
| - (1881541) | 1881541..1881607 | + | 67 | NuclAT_29 | - | Antitoxin |
| PO910_RS09105 (1881921) | 1881921..1882028 | - | 108 | WP_000170926.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_32 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_32 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_32 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_32 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_35 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_35 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_35 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_35 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_38 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_38 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_38 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_38 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_41 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_41 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_41 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_41 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_44 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_44 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_44 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_44 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_47 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_47 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_47 | - | - |
| - (1882081) | 1882081..1882142 | + | 62 | NuclAT_47 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_15 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_15 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_15 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_15 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_18 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_18 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_18 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_18 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_21 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_21 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_21 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_21 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_24 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_24 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_24 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_24 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_27 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_27 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_27 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_27 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_30 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_30 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_30 | - | - |
| - (1882081) | 1882081..1882143 | + | 63 | NuclAT_30 | - | - |
| - (1882081) | 1882081..1882144 | + | 64 | NuclAT_50 | - | - |
| - (1882081) | 1882081..1882144 | + | 64 | NuclAT_50 | - | - |
| - (1882081) | 1882081..1882144 | + | 64 | NuclAT_50 | - | - |
| - (1882081) | 1882081..1882144 | + | 64 | NuclAT_50 | - | - |
| - (1882081) | 1882081..1882144 | + | 64 | NuclAT_52 | - | - |
| - (1882081) | 1882081..1882144 | + | 64 | NuclAT_52 | - | - |
| - (1882081) | 1882081..1882144 | + | 64 | NuclAT_52 | - | - |
| - (1882081) | 1882081..1882144 | + | 64 | NuclAT_52 | - | - |
| PO910_RS09110 (1882457) | 1882457..1882564 | - | 108 | WP_000170926.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_33 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_33 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_33 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_33 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_36 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_36 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_36 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_36 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_39 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_39 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_39 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_39 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_42 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_42 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_42 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_42 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_45 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_45 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_45 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_45 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_48 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_48 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_48 | - | - |
| - (1882617) | 1882617..1882678 | + | 62 | NuclAT_48 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_16 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_16 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_16 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_16 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_19 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_19 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_19 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_19 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_22 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_22 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_22 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_22 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_25 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_25 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_25 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_25 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_28 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_28 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_28 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_28 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_31 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_31 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_31 | - | - |
| - (1882617) | 1882617..1882679 | + | 63 | NuclAT_31 | - | - |
| - (1882617) | 1882617..1882680 | + | 64 | NuclAT_51 | - | - |
| - (1882617) | 1882617..1882680 | + | 64 | NuclAT_51 | - | - |
| - (1882617) | 1882617..1882680 | + | 64 | NuclAT_51 | - | - |
| - (1882617) | 1882617..1882680 | + | 64 | NuclAT_51 | - | - |
| - (1882617) | 1882617..1882680 | + | 64 | NuclAT_53 | - | - |
| - (1882617) | 1882617..1882680 | + | 64 | NuclAT_53 | - | - |
| - (1882617) | 1882617..1882680 | + | 64 | NuclAT_53 | - | - |
| - (1882617) | 1882617..1882680 | + | 64 | NuclAT_53 | - | - |
| PO910_RS09115 (1882970) | 1882970..1884070 | - | 1101 | WP_001295620.1 | sodium-potassium/proton antiporter ChaA | - |
| PO910_RS09120 (1884340) | 1884340..1884570 | + | 231 | WP_001146442.1 | putative cation transport regulator ChaB | - |
| PO910_RS09125 (1884728) | 1884728..1885423 | + | 696 | WP_001355927.1 | glutathione-specific gamma-glutamylcyclotransferase | - |
| PO910_RS09130 (1885467) | 1885467..1885820 | - | 354 | WP_001169669.1 | DsrE/F sulfur relay family protein YchN | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3983.80 Da Isoelectric Point: 11.4779
>T269618 WP_000170954.1 NZ_CP116981:c1881493-1881386 [Escherichia coli]
MTLAQFAMIFWHDLAAPILAGIITAAIVGWWRNRK
MTLAQFAMIFWHDLAAPILAGIITAAIVGWWRNRK
Download Length: 108 bp
Antitoxin
Download Length: 67 bp
>AT269618 NZ_CP116981:1881541-1881607 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTC
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTC
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
