Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 36057..36326 Replicon plasmid pCUVM3.4
Accession NZ_CP116974
Organism Escherichia coli strain CUVM3

Toxin (Protein)


Gene name hok Uniprot ID -
Locus tag PQP09_RS26290 Protein ID WP_001372321.1
Coordinates 36201..36326 (+) Length 42 a.a.

Antitoxin (RNA)


Gene name sok
Locus tag -
Coordinates 36057..36122 (-)

Genomic Context

PQP09_RS26255PQP09_RS26260PQP09_RS26265PQP09_RS26270PQP09_RS26275----PQP09_RS26285PQP09_RS26290PQP09_RS26315PQP09_RS26320PQP09_RS26280--PQP09_RS26295PQP09_RS26300PQP09_RS26305PQP09_RS26310
Location: 31767..32294 (528 bp)
Type: Others
Protein ID: WP_000290834.1
Location: 32352..32585 (234 bp)
Type: Others
Protein ID: WP_000006003.1
Location: 32646..34669 (2024 bp)
Type: Others
Protein ID: Protein_43
Location: 34738..35172 (435 bp)
Type: Others
Protein ID: WP_000845953.1
Location: 35169..35931 (763 bp)
Type: Others
Protein ID: Protein_45
Location: 35900..36124 (225 bp)
Type: Others
Protein ID: NuclAT_0
Location: 35900..36124 (225 bp)
Type: Others
Protein ID: NuclAT_0
Location: 35900..36124 (225 bp)
Type: Others
Protein ID: NuclAT_0
Location: 35900..36124 (225 bp)
Type: Others
Protein ID: NuclAT_0
Location: 36110..36259 (150 bp)
Type: Others
Protein ID: Protein_47
Location: 36201..36326 (126 bp)
Type: Toxin
Protein ID: WP_001372321.1
Location: 39953..40249 (297 bp)
Type: Others
Protein ID: WP_001272251.1
Location: 40360..41181 (822 bp)
Type: Others
Protein ID: WP_001234445.1
Location: 35909..36088 (180 bp)
Type: Others
Protein ID: WP_001309233.1
Location: 36057..36122 (66 bp)
Type: Antitoxin
Protein ID: -
Location: 36628..38199 (1572 bp)
Type: Others
Protein ID: WP_094083869.1
Location: 38219..38566 (348 bp)
Type: Others
Protein ID: WP_000624622.1
Location: 38566..39216 (651 bp)
Type: Others
Protein ID: WP_000993956.1
Location: 39357..39653 (297 bp)
Type: Others
Protein ID: Protein_52
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PQP09_RS2625531767..32294+528WP_000290834.1single-stranded DNA-binding protein-
PQP09_RS2626032352..32585+234WP_000006003.1DUF905 family protein-
PQP09_RS2626532646..34669+2024Protein_43ParB/RepB/Spo0J family partition protein-
PQP09_RS2627034738..35172+435WP_000845953.1conjugation system SOS inhibitor PsiB-
PQP09_RS2627535169..35931+763Protein_45plasmid SOS inhibition protein A-
-35900..36124+225NuclAT_0--
-35900..36124+225NuclAT_0--
-35900..36124+225NuclAT_0--
-35900..36124+225NuclAT_0--
PQP09_RS2628035909..36088-180WP_001309233.1hypothetical protein-
-36057..36122-66--Antitoxin
PQP09_RS2628536110..36259+150Protein_47plasmid maintenance protein Mok-
PQP09_RS2629036201..36326+126WP_001372321.1type I toxin-antitoxin system Hok family toxinToxin
PQP09_RS2629536628..38199-1572WP_094083869.1IS66-like element ISCro1 family transposase-
PQP09_RS2630038219..38566-348WP_000624622.1IS66 family insertion sequence element accessory protein TnpB-
PQP09_RS2630538566..39216-651WP_000993956.1IS66-like element accessory protein TnpA-
PQP09_RS2631039357..39653-297Protein_52hypothetical protein-
PQP09_RS2631539953..40249+297WP_001272251.1hypothetical protein-
PQP09_RS2632040360..41181+822WP_001234445.1DUF932 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(2-37)


Sequences

Toxin        


Download         Length: 42 a.a.        Molecular weight: 4780.69 Da        Isoelectric Point: 8.5110

>T269584 WP_001372321.1 NZ_CP116974:36201-36326 [Escherichia coli]
VLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAAFMAYESGK

Download         Length: 126 bp

Antitoxin


Download         Length: 66 bp

>AT269584 NZ_CP116974:c36122-36057 [Escherichia coli]
GTGGACTAGACATAGGGATGCCTCGTGGTGGTTAATGAAAATTAACTTACTACGGGGCTATCTTCT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

Download structure file

References