Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 2771249..2771840 | Replicon | chromosome |
Accession | NC_017538 | ||
Organism | Oligotropha carboxidovorans OM4 |
Toxin (Protein)
Gene name | higB | Uniprot ID | B6JBF6 |
Locus tag | OCA4_RS13190 | Protein ID | WP_012562526.1 |
Coordinates | 2771249..2771530 (+) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | OCA4_RS13195 | Protein ID | WP_012562525.1 |
Coordinates | 2771541..2771840 (+) | Length | 100 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OCA4_RS13170 | 2766536..2768344 | - | 1809 | WP_012562530.1 | flagellar hook-basal body complex protein | - |
OCA4_RS13175 | 2768523..2769017 | - | 495 | WP_012562529.1 | peptide-methionine (R)-S-oxide reductase MsrB | - |
OCA4_RS13180 | 2769110..2770513 | - | 1404 | WP_012562528.1 | FAD-binding oxidoreductase | - |
OCA4_RS13185 | 2770629..2771159 | + | 531 | WP_012562527.1 | histidine phosphatase family protein | - |
OCA4_RS13190 | 2771249..2771530 | + | 282 | WP_012562526.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
OCA4_RS13195 | 2771541..2771840 | + | 300 | WP_012562525.1 | HigA family addiction module antidote protein | Antitoxin |
OCA4_RS13200 | 2771982..2772425 | + | 444 | WP_041559641.1 | hypothetical protein | - |
OCA4_RS13205 | 2772465..2772971 | - | 507 | WP_013913263.1 | ferritin-like domain-containing protein | - |
OCA4_RS13210 | 2773377..2774435 | + | 1059 | WP_012562521.1 | flippase-like domain-containing protein | - |
OCA4_RS13215 | 2774486..2776459 | + | 1974 | WP_012562520.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10569.07 Da Isoelectric Point: 10.2043
>T26957 WP_012562526.1 NC_017538:2771249-2771530 [Afipia carboxidovorans OM4]
VIKSFKDDLTEAAFNGKARKGFPAQLLKVARRKLAMVNAATSLDDLRSPPNNRLEALTRERAGQHSIRVNDQFRICFIWT
KDGAEQVELVDYH
VIKSFKDDLTEAAFNGKARKGFPAQLLKVARRKLAMVNAATSLDDLRSPPNNRLEALTRERAGQHSIRVNDQFRICFIWT
KDGAEQVELVDYH
Download Length: 282 bp
>T26957 NC_017538:2771249-2771530 [Afipia carboxidovorans OM4]
GTGATCAAGAGCTTCAAGGACGATCTGACTGAAGCAGCCTTCAACGGGAAGGCACGCAAAGGTTTTCCGGCTCAGTTACT
CAAAGTTGCCCGCCGCAAACTGGCGATGGTGAATGCGGCTACATCCCTGGATGATCTGCGTTCGCCGCCCAACAACCGAC
TTGAAGCTCTCACCAGGGAGCGAGCGGGCCAGCATTCAATTCGGGTGAACGACCAGTTTCGCATCTGCTTCATATGGACG
AAGGATGGAGCTGAACAAGTCGAGCTTGTCGATTATCATTAG
GTGATCAAGAGCTTCAAGGACGATCTGACTGAAGCAGCCTTCAACGGGAAGGCACGCAAAGGTTTTCCGGCTCAGTTACT
CAAAGTTGCCCGCCGCAAACTGGCGATGGTGAATGCGGCTACATCCCTGGATGATCTGCGTTCGCCGCCCAACAACCGAC
TTGAAGCTCTCACCAGGGAGCGAGCGGGCCAGCATTCAATTCGGGTGAACGACCAGTTTCGCATCTGCTTCATATGGACG
AAGGATGGAGCTGAACAAGTCGAGCTTGTCGATTATCATTAG
Antitoxin
Download Length: 100 a.a. Molecular weight: 10856.59 Da Isoelectric Point: 9.0146
>AT26957 WP_012562525.1 NC_017538:2771541-2771840 [Afipia carboxidovorans OM4]
MAKTLPPLHPGEVLREEYLEPLNLSPGKLAKACGIPRTRIERIASERFGITADTALRLGKALGTSAQFWLNLQNDYDLRV
AKVAIAKDLEKVTSVQEAA
MAKTLPPLHPGEVLREEYLEPLNLSPGKLAKACGIPRTRIERIASERFGITADTALRLGKALGTSAQFWLNLQNDYDLRV
AKVAIAKDLEKVTSVQEAA
Download Length: 300 bp
>AT26957 NC_017538:2771541-2771840 [Afipia carboxidovorans OM4]
ATGGCCAAGACACTGCCGCCACTGCACCCCGGGGAAGTTCTTCGGGAAGAATATCTGGAGCCGCTGAATCTCTCGCCCGG
CAAACTTGCCAAGGCCTGTGGCATTCCCCGTACGCGCATCGAGCGTATCGCCAGCGAGCGTTTCGGCATTACCGCAGACA
CTGCTCTACGACTCGGCAAGGCGCTCGGTACTTCCGCCCAGTTCTGGCTCAACCTGCAGAATGACTACGATCTGCGGGTG
GCAAAAGTGGCAATCGCGAAGGATCTGGAAAAGGTCACCTCCGTTCAAGAGGCCGCCTAG
ATGGCCAAGACACTGCCGCCACTGCACCCCGGGGAAGTTCTTCGGGAAGAATATCTGGAGCCGCTGAATCTCTCGCCCGG
CAAACTTGCCAAGGCCTGTGGCATTCCCCGTACGCGCATCGAGCGTATCGCCAGCGAGCGTTTCGGCATTACCGCAGACA
CTGCTCTACGACTCGGCAAGGCGCTCGGTACTTCCGCCCAGTTCTGGCTCAACCTGCAGAATGACTACGATCTGCGGGTG
GCAAAAGTGGCAATCGCGAAGGATCTGGAAAAGGTCACCTCCGTTCAAGAGGCCGCCTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|