Detailed information of TA system TA269540

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 429053..429277
• Replicon: chromosome
• Accession: NZ_CP116962
• Organism: Enterococcus faecalis strain DM86

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: PO880_RS01975
• Protein ID: WP_021164442.1
• Coordinates: 429053..429154 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	429091..429277 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PO880_RS01955	424380..424778	+	399	WP_002354951.1	glyoxalase	-
PO880_RS01960	424829..425725	-	897	WP_002365354.1	YitT family protein	-
PO880_RS01965	425915..426421	-	507	WP_010710886.1	cysteine hydrolase family protein	-
PO880_RS01970	426592..428862	+	2271	WP_002368430.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
PO880_RS01975	429053..429154	+	102	WP_021164442.1	putative holin-like toxin	Toxin
-	429091..429277	-	187	-	-	Antitoxin
PO880_RS01980	429340..429792	-	453	WP_010710887.1	YueI family protein	-
PO880_RS01985	429977..430924	+	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
PO880_RS01990	430921..431886	+	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
PO880_RS01995	431883..432638	+	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
PO880_RS02000	432677..433630	+	954	WP_002408267.1	siderophore ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3625.38 Da
• Isoelectric Point: 4.5869

>T269540 WP_021164442.1 NZ_CP116962:429053-429154 [Enterococcus faecalis]
MSIEATLELMISFATLVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 187 bp

>AT269540 NZ_CP116962:c429277-429091 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTT
TTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCG
AAAATCAGTAACGCAACAAGGGTTGCA

Structures

Antitoxin