Detailed information of TA system TA269377

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 925049..925229
• Replicon: chromosome
• Accession: NZ_CP116909
• Organism: Staphylococcus aureus strain AATYW

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: LOY12_RS04980
• Protein ID: WP_001801861.1
• Coordinates: 925134..925229 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	925049..925106 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LOY12_RS04950	920758..920892	+	135	WP_001791797.1	hypothetical protein	-
LOY12_RS04955	921056..922612	+	1557	WP_000028669.1	type I restriction-modification system subunit M	-
LOY12_RS04960	922605..923834	+	1230	WP_000072627.1	restriction endonuclease subunit S	-
LOY12_RS04965	924376..924786	+	411	WP_001808705.1	IS21 family transposase	-
LOY12_RS04970	924771..924932	+	162	Protein_940	transposase	-
LOY12_RS04975	924910..925011	-	102	WP_001792025.1	hypothetical protein	-
-	925049..925106	+	58	-	-	Antitoxin
LOY12_RS04980	925134..925229	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
LOY12_RS04985	925374..926386	+	1013	Protein_943	IS3 family transposase	-
LOY12_RS04990	926584..927156	-	573	WP_000414216.1	hypothetical protein	-
LOY12_RS04995	927257..927598	-	342	WP_000627540.1	DUF3969 family protein	-
LOY12_RS05000	927639..928265	-	627	WP_000669024.1	hypothetical protein	-
LOY12_RS05005	928340..929335	-	996	WP_000070642.1	DUF4352 domain-containing protein	-
LOY12_RS05010	929416..930066	-	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hlgA / lukD	898216..948853	50637

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T269377 WP_001801861.1 NZ_CP116909:c925229-925134 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT269377 NZ_CP116909:925049-925106 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin