Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 584031..584293 Replicon chromosome
Accession NZ_CP116909
Organism Staphylococcus aureus strain AATYW

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag LOY12_RS02880 Protein ID WP_001802298.1
Coordinates 584031..584135 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 584130..584293 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY12_RS02865 580828..581610 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
LOY12_RS02870 581678..582535 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
LOY12_RS02875 583193..583351 - 159 WP_001792784.1 hypothetical protein -
LOY12_RS02880 584031..584135 + 105 WP_001802298.1 hypothetical protein Toxin
- 584130..584293 - 164 - - Antitoxin
LOY12_RS02890 584568..585659 - 1092 WP_000495669.1 hypothetical protein -
LOY12_RS02895 585925..586902 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
LOY12_RS02900 586904..587224 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LOY12_RS02905 587376..588041 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T269367 WP_001802298.1 NZ_CP116909:584031-584135 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 164 bp

>AT269367 NZ_CP116909:c584293-584130 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References