Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 298638..298822 Replicon chromosome
Accession NZ_CP116909
Organism Staphylococcus aureus strain AATYW

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag LOY12_RS01400 Protein ID WP_000482652.1
Coordinates 298638..298745 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 298762..298822 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY12_RS01375 294000..294473 + 474 WP_000456486.1 GyrI-like domain-containing protein -
LOY12_RS01380 294596..295807 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
LOY12_RS01385 295989..296648 - 660 WP_000831298.1 membrane protein -
LOY12_RS01390 296708..297850 - 1143 WP_001176863.1 glycerate kinase -
LOY12_RS01395 298118..298504 + 387 WP_000779360.1 flippase GtxA -
LOY12_RS01400 298638..298745 + 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
- 298762..298822 - 61 - - Antitoxin
LOY12_RS01405 299448..301211 + 1764 WP_001064825.1 ABC transporter ATP-binding protein -
LOY12_RS01410 301236..302969 + 1734 WP_000486487.1 ABC transporter ATP-binding protein -
LOY12_RS01415 303236..303367 + 132 WP_223197975.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T269365 WP_000482652.1 NZ_CP116909:298638-298745 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT269365 NZ_CP116909:c298822-298762 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References