Detailed information of TA system TA269278

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 1722753..1722999
• Replicon: chromosome
• Accession: NZ_CP116865
• Organism: Bacillus subtilis subsp. subtilis strain MGP016

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: PPM43_RS08820
• Protein ID: WP_109789044.1
• Coordinates: 1722753..1722845 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	1722826..1722999 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PPM43_RS08805	1717912..1718247	+	336	WP_009967409.1	hypothetical protein	-
PPM43_RS08810	1718294..1721899	-	3606	WP_004399367.1	P-loop NTPase fold protein	-
PPM43_RS08815	1722132..1722464	-	333	WP_026009814.1	hypothetical protein	-
PPM43_RS08820	1722753..1722845	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	1722826..1722999	-	174	-	-	Antitoxin
PPM43_RS08825	1723114..1723956	-	843	WP_003231327.1	hypothetical protein	-
PPM43_RS08830	1724156..1724614	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
PPM43_RS08835	1724624..1726426	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
PPM43_RS08840	1726528..1727085	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1708738..1732416	23678

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T269278 WP_109789044.1 NZ_CP116865:1722753-1722845 [Bacillus subtilis subsp. subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT269278 NZ_CP116865:c1722999-1722826 [Bacillus subtilis subsp. subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin