Detailed information of TA system TA269270

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 1664344..1664590
• Replicon: chromosome
• Accession: NZ_CP116863
• Organism: Bacillus subtilis subsp. subtilis strain MGP027

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: PPM47_RS08715
• Protein ID: WP_109789044.1
• Coordinates: 1664344..1664436 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	1664417..1664590 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PPM47_RS08700	1659503..1659838	+	336	WP_009967409.1	hypothetical protein	-
PPM47_RS08705	1659885..1663490	-	3606	WP_004399367.1	P-loop NTPase fold protein	-
PPM47_RS08710	1663723..1664055	-	333	WP_026009814.1	hypothetical protein	-
PPM47_RS08715	1664344..1664436	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	1664417..1664590	-	174	-	-	Antitoxin
PPM47_RS08720	1664705..1665547	-	843	WP_003231327.1	hypothetical protein	-
PPM47_RS08725	1665747..1666205	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
PPM47_RS08730	1666215..1668017	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
PPM47_RS08735	1668119..1668676	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1650739..1690246	39507

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T269270 WP_109789044.1 NZ_CP116863:1664344-1664436 [Bacillus subtilis subsp. subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT269270 NZ_CP116863:c1664590-1664417 [Bacillus subtilis subsp. subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin