269251

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 5172525..5173060 Replicon chromosome
Accession NZ_CP116806
Organism Streptomyces sp. JCM 35825

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PPN52_RS23810 Protein ID WP_230902546.1
Coordinates 5172806..5173060 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PPN52_RS23805 Protein ID WP_230902545.1
Coordinates 5172525..5172809 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PPN52_RS23785 (PPN52_23785) 5168627..5169619 + 993 WP_230902541.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
PPN52_RS23790 (PPN52_23790) 5169642..5170385 + 744 WP_230902542.1 ROK family protein -
PPN52_RS23795 (PPN52_23795) 5170430..5171059 - 630 WP_230902543.1 hypothetical protein -
PPN52_RS23800 (PPN52_23800) 5171284..5172372 + 1089 WP_230902544.1 redox-regulated ATPase YchF -
PPN52_RS23805 (PPN52_23805) 5172525..5172809 + 285 WP_230902545.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PPN52_RS23810 (PPN52_23810) 5172806..5173060 + 255 WP_230902546.1 Txe/YoeB family addiction module toxin Toxin
PPN52_RS23815 (PPN52_23815) 5173230..5174408 - 1179 WP_230902547.1 serine/threonine-protein kinase -
PPN52_RS23820 (PPN52_23820) 5174408..5176180 - 1773 WP_230902548.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-65)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10099.60 Da        Isoelectric Point: 7.3149

>T269251 WP_230902546.1 NZ_CP116806:5172806-5173060 [Streptomyces sp. JCM 35825]
VRLVFEDQGWEDYTSWLKDDRKMLARINKLIEDVKRDPFTGIGKPEPLKYHLPGAWSRRIDDEHRLVYLVTDKEIVILAA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10095.25 Da        Isoelectric Point: 4.6652

>AT269251 WP_230902545.1 NZ_CP116806:5172525-5172809 [Streptomyces sp. JCM 35825]
MSITASEARKALFPLIKKVNDDHEAIEIVSKHGNAVLVSAEDYAALREGSYLLRSPANARRLLRAYENALGDSNVSEREL
IDPDSADVAGEGAA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References