Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5104361..5105022 Replicon chromosome
Accession NZ_CP116775
Organism Pseudomonas sp. 273

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PKO50_RS23225 Protein ID WP_275627345.1
Coordinates 5104675..5105022 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PKO50_RS23220 Protein ID WP_089391836.1
Coordinates 5104361..5104678 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PKO50_RS23195 5099402..5100166 - 765 WP_089391832.1 arginine/ornithine transport ATP-binding protein AotP -
PKO50_RS23200 5100182..5101294 - 1113 WP_275627344.1 M14 family metallopeptidase -
PKO50_RS23205 5101311..5102009 - 699 WP_089391834.1 ABC transporter permease -
PKO50_RS23210 5102023..5102712 - 690 WP_109931925.1 ABC transporter permease -
PKO50_RS23215 5102881..5103660 - 780 WP_009620740.1 ABC transporter substrate-binding protein -
PKO50_RS23220 5104361..5104678 - 318 WP_089391836.1 transcriptional regulator Antitoxin
PKO50_RS23225 5104675..5105022 - 348 WP_275627345.1 toxin Toxin
PKO50_RS23230 5105181..5107136 - 1956 WP_275627346.1 acetate--CoA ligase -
PKO50_RS23235 5107286..5108566 - 1281 WP_109931917.1 C4-dicarboxylate TRAP transporter large permease protein DctM -
PKO50_RS23240 5108563..5109195 - 633 WP_109931915.1 TRAP transporter small permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-92)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13320.24 Da        Isoelectric Point: 10.1328

>T269244 WP_275627345.1 NZ_CP116775:c5105022-5104675 [Pseudomonas sp. 273]
MKAAFVELSPFERNRRHYLDDEAFRLFQQLLLARPDAGDVIAGTGGLRKVRFGDPGRGKGRRGGLRVIYYCWLGSAQFWL
FTLYDKDEQDDLNERQRNQLAVLLQAELKSRGMVR

Download         Length: 348 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11849.64 Da        Isoelectric Point: 6.7293

>AT269244 WP_089391836.1 NZ_CP116775:c5104678-5104361 [Pseudomonas sp. 273]
MSKRDIFAELLEGFDDLAAERQGKITLRTHKVESAPLLPATGEEIAALRERLNMSQPVFARILHAAPATLKNWEQNRSRP
NDQATLLIRLLARHPETLELITELA

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References